منابع مشابه
comparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولThe Prevalence of Drug-Drug Interaction and Inappropriate Drug Prescription Among the Elderly in Kashan
Background: Drug-drug Interaction (DDI) among the elderly is one of the major healthcare challenges worldwide. The present study assessed the rates of DDI and inappropriate drug prescription among the elderly in Kashan City, Iran. Methods: This descriptive-analytical study was designed, conducted, and reported according to the guideline of Strengthening the Reporting of Observational Studies ...
متن کاملDrug-drug interaction prediction assessment.
Model-based drug-drug interaction (DDI) is an important in-silico tool to assess the in vivo consequences of in vitro DDI. Before its general application to new drug compounds, the DDI model is always established from known interaction data. For the first time, tests for difference and equivalent tests are implemented to compare reported and model-base simulated DDI (log AUCR) in the sample mea...
متن کاملDrug-Drug Interaction Pattern Recognition
BACKGROUND AND OBJECTIVE Drug-drug interaction (DDI) is an important aspect of drug development, especially for safety. When a drug is used concomitantly with other drug(s), one of the major concerns is the change of exposures, including the rate and extent of drug absorption, distribution, metabolism and elimination. To address the concerns, a common practice is to measure and report the diffe...
متن کاملDrug-Drug Interaction Clinical Decision Support Systems: Advantages, Challenges and Barriers, and Strategies to Overcome Them
Drug-drug interactions (DDIs) are a common source of preventable medical errors in inpatient and outpatient settings of both developed and developing countries. When two or more drugs are simultaneously prescribed, interactions between their effects may result in preventable adverse events such as damages to vital organs, frequent hospitalizations, prolonged length of hospital stay, and increas...
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ژورنال
عنوان ژورنال: Jornal Brasileiro de Nefrologia
سال: 2014
ISSN: 0101-2800
DOI: 10.5935/0101-2800.20140003